Optoacoustic tomography: Systems and theory

Optoacoustic tomography (OAT), also known as photoacoustic tomography, is a hybrid imaging modality that enables the visualization of optical contrast with high resolution at tissue depths in which light propagation is diffusive. In multi-spectral optoacoustic tomography (MSOT), the optical excitation is performed in several wavelengths, enabling the detection of various chromophores based on their spectral signature and quantifying oxygen saturation in tissue. The additional dimension offered by MSOT makes it a highly promising technique for pre-clinical research and clinical applications.

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